WaterView is DesertSci’s latest module for the Proasis system, identifing preferred locations for hydrogen bond donors and acceptors in a binding site.
In drug discovery, significant gains in affinity and selectivity can be acheived by targeting the right waters
Waterview is a robust method for better understanding the role of waters in ligand binding. Based on solid experimentally derived data, both the preferred locations of binding site waters and thier local distributions can be highlighted.
Descriptors are derived from high quality overlays and a density based clustering approach.
WaterView seamlessly links Proasis3 and Profusion functionality, to provide you with an improved understanding of waters in a binding site.
For more information on the WaterView module please download our brochure below, or contacts us at email@example.com
WaterView Brochure (849 KB)