Flexibility Prediction Tool

DesertSci’s flexibility prediction tool is designed for exploring the flexibility of key residues in binding sites in new protein crystal structures.

We have created an empirical model, with calculations done using atom level data derived from experiment and Scorpion network parameters. The model has been parameterised according to a data set of very high quality protein crystal structure overlays.

This tool is very easy to use within the Proasis3 interface and as a ProasisAPI resource.  It is also available to Viper users, as part of the ViperWeb interface.