The reporting functionality of Proasis4 has been greatly extended with the addition of the new option of Clustering Binding Site Atoms.
For any set of overlaid structures in Proasis4, a comprehensive report is compiled that includes:
Two distinct clustering reports are created:
Reports can be created listing:
The new clustering report type provides a great deal of new information that was previously quite difficult to obtain, including details about binding site residue positions that are disordered or have distinct conformations.
This latest Proasis4 extension provides a powerful new analysis tool that contributes key insights about protein targets for structure based drug design.